Development of drug-inducible CRISPR-Cas9 systems for large-scale functional screening

Development of drug-inducible CRISPR-Cas9 systems for large-scale functional screening

Abstract Background Large-scale genetic screening using CRISPR-Cas9 technology has emerged as a powerful approach to uncover and validate gene functions. The ability to control the timing of genetic perturbation during CRISPR screens will facilitate precise dissection of dynamic and complex biologic...

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Bibliographic Details
Main Authors: Ning Sun, Sakina Petiwala, Rui Wang, Charles Lu, Mufeng Hu, Sujana Ghosh, Yan Hao, Christopher P. Miller, Namjin Chung
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Genomics
Subjects:
CRISPR
Gene editing
Functional genomics
Online Access:http://link.springer.com/article/10.1186/s12864-019-5601-9

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http://link.springer.com/article/10.1186/s12864-019-5601-9

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