Activation of multiple Eph receptors on neuronal membranes correlates with the onset of optic neuropathy

Activation of multiple Eph receptors on neuronal membranes correlates with the onset of optic neuropathy

Abstract Background Optic neuropathy is a major cause of irreversible blindness, yet the molecular determinants that contribute to neuronal demise have not been fully elucidated. Several studies have identified ‘ephrin signaling’ as one of the most dysregulated pathways in the early pathophysiology...

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Bibliographic Details
Main Authors: Thomas A. Strong, Juan Esquivel, Qikai Wang, Paul J. Ledon, Hua Wang, Gabriel Gaidosh, David Tse, Daniel Pelaez
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Eye and Vision
Subjects:
Optic neuropathy
Ephrin signaling
Eph receptor
Axonal guidance
Neuropathy
Neurodegeneration
Online Access:https://doi.org/10.1186/s40662-023-00359-w

Internet

https://doi.org/10.1186/s40662-023-00359-w

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