Protection from SARS-CoV-2 Variants by MVAs expressing matched or mismatched S administered intranasally to mice

Abstract SARS-CoV-2 vaccines prevent severe disease but are less efficient in averting infection and transmission of variant strains, making it imperative to explore ways of enhancing protection. Use of inbred mice expressing the human SARS-CoV-2 receptor facilitates such investigations. We employed...

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Bibliographic Details
Main Authors: Catherine A. Cotter, Jeffrey L. Americo, Patricia L. Earl, Bernard Moss
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00645-7