Protection from SARS-CoV-2 Variants by MVAs expressing matched or mismatched S administered intranasally to mice
Abstract SARS-CoV-2 vaccines prevent severe disease but are less efficient in averting infection and transmission of variant strains, making it imperative to explore ways of enhancing protection. Use of inbred mice expressing the human SARS-CoV-2 receptor facilitates such investigations. We employed...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-03-01
|
Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-023-00645-7 |