Exerkine β-aminoisobutyric acid protects against atrial structural remodeling and atrial fibrillation in obesity via activating AMPK signaling and improving insulin sensitivity

Exerkine β-aminoisobutyric acid protects against atrial structural remodeling and atrial fibrillation in obesity via activating AMPK signaling and improving insulin sensitivity

Moderate exercise decreases the risk for atrial fibrillation (AF), an effect which is probably mediated via exercise-stimulated release of exerkines. β-Aminoisobutyric acid (BAIBA), a novel exerkine, has been reported to provide protective benefits against many cardiovascular diseases, yet its role...

Full description

Bibliographic Details
Main Authors: Xinghua Qin, Peng Liu, Lingyan Jin, Ke Zhu, Yuanqing Yang, Zuoxu Hou, Huiliang Zhang, Qiangsun Zheng
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Atrial fibrillation
β-Aminoisobutyric Acid
Metabolic flexibility
Insulin resistance
AMP-activated protein kinase
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224000180

Internet

http://www.sciencedirect.com/science/article/pii/S0753332224000180

Similar Items