The Development of a Pipeline for the Identification and Validation of Small-Molecule RelA Inhibitors for Use as Anti-Biofilm Drugs

Biofilm infections have no approved effective medical treatments and can only be disrupted via physical means. This means that any biofilm infection that is not addressable surgically can never be eliminated and can only be managed as a chronic disease. Therefore, there is an urgent need for the dev...

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Bibliographic Details
Main Authors: Donald C. Hall, Jarosław E. Król, John P. Cahill, Hai-Feng Ji, Garth D. Ehrlich
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/8/9/1310