The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

Fibroblast growth factor-21 (FGF21) is a hormone secreted by the liver during fasting that elicits diverse aspects of the adaptive starvation response. Among its effects, FGF21 induces hepatic fatty acid oxidation and ketogenesis, increases insulin sensitivity, blocks somatic growth and causes bone...

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Bibliografische gegevens
Hoofdauteurs: Yuan Zhang, Yang Xie, Eric D Berglund, Katie Colbert Coate, Tian Teng He, Takeshi Katafuchi, Guanghua Xiao, Matthew J Potthoff, Wei Wei, Yihong Wan, Ruth T Yu, Ronald M Evans, Steven A Kliewer, David J Mangelsdorf
Formaat: Artikel
Taal:English
Gepubliceerd in: eLife Sciences Publications Ltd 2012-10-01
Reeks:eLife
Onderwerpen:
longevity
fibroblast growth factor
growth hormone
liver
caloric restriction
Online toegang:https://elifesciences.org/articles/00065

Internet

https://elifesciences.org/articles/00065

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