Gelatin methacryloyl (GelMA) loaded with concentrated hypoxic pretreated adipose-derived mesenchymal stem cells(ADSCs) conditioned medium promotes wound healing and vascular regeneration in aged skin

Gelatin methacryloyl (GelMA) loaded with concentrated hypoxic pretreated adipose-derived mesenchymal stem cells(ADSCs) conditioned medium promotes wound healing and vascular regeneration in aged skin

Abstract Background Aging skin is characterized by a disturbed structure and lack of blood supply, which makes it difficult to heal once injured. ADSCs secrete large amounts of cytokines, which promote wound healing and vascular regeneration through paracrine secretion, and the number of cytokines c...

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Bibliographic Details
Main Authors: Shiyi Li, Jiachen Sun, Jinxiu Yang, Yi Yang, Hongfan Ding, Boya Yu, Kui Ma, Minliang Chen
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2023-02-01
Series:Biomaterials Research
Subjects:
Aged wound
Angiogenesis
GelMA hydrogel
ADSCs
Conditioned medium
Hypoxia
Online Access:https://doi.org/10.1186/s40824-023-00352-3

Internet

https://doi.org/10.1186/s40824-023-00352-3

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