The tell-tale heart: population-based surveillance reveals an association of rofecoxib and celecoxib with myocardial infarction.

COX-2 selective inhibitors are associated with myocardial infarction (MI). We sought to determine whether population health monitoring would have revealed the effect of COX-2 inhibitors on population-level patterns of MI.We conducted a retrospective study of inpatients at two Boston hospitals, from...

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Bibliographic Details
Main Authors: John S Brownstein, Margarita Sordo, Isaac S Kohane, Kenneth D Mandl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1950690?pdf=render