Over-expression of PDGFR-β promotes PDGF-induced proliferation, migration, and angiogenesis of EPCs through PI3K/Akt signaling pathway.

Over-expression of PDGFR-β promotes PDGF-induced proliferation, migration, and angiogenesis of EPCs through PI3K/Akt signaling pathway.

The proliferation, migration, and angiogenesis of endothelial progenitor cells (EPCs) play critical roles in postnatal neovascularization and re-endothelialization following vascular injury. Here we evaluated whether the over-expression of platelet-derived growth factor receptor-β (PDGFR-β) can enha...

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Bibliographic Details
Main Authors: Hang Wang, Yangguang Yin, Wei Li, Xiaohui Zhao, Yang Yu, Jinkun Zhu, Zhexue Qin, Qiang Wang, Kui Wang, Wei Lu, Jie Liu, Lan Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3280261?pdf=render

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http://europepmc.org/articles/PMC3280261?pdf=render

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