P4.4 INHIBITION OF ARTERIAL CALCIFICATION BY MATRIX GLA PROTEIN AS DETERMINANT OF RENAL FUNCTION IN THE GENERAL POPULATION

P4.4 INHIBITION OF ARTERIAL CALCIFICATION BY MATRIX GLA PROTEIN AS DETERMINANT OF RENAL FUNCTION IN THE GENERAL POPULATION

Background: Carboxylation of matrix Gla protein (MGP), a vitamin K dependent process, activates the protein to a powerful inhibitor of arterial calcification. Circulating dephosphorylated and uncarboxylated MGP (dp-ucMGP) and total uncarboxylated MGP (t-ucMGP) are associated with macrovascular disea...

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Bibliographic Details
Main Authors: Fangfei Wei*, Nadja E.A. Drummen, Lutgarde Thijs, Lotte Jacobs, Marjo H.J. Knapen, Thibaut Petit, Wenyi Yang, Zhenyu Zhang, Yumei Gu, Tatiana Kuznetsova, Peter Verhamme, Pieter Evenepoel, Cees Vermeer, Jan A. Staessen
Format: Article
Language:English
Published: BMC 2015-11-01
Series:Artery Research
Online Access:https://www.atlantis-press.com/article/125930611/view

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https://www.atlantis-press.com/article/125930611/view

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