Expert workshop summary: Advancing toward a standardized murine model to evaluate treatments for antimicrobial resistance lung infections

Expert workshop summary: Advancing toward a standardized murine model to evaluate treatments for antimicrobial resistance lung infections

The rise in antimicrobial resistance (AMR), and increase in treatment-refractory AMR infections, generates an urgent need to accelerate the discovery and development of novel anti-infectives. Preclinical animal models play a crucial role in assessing the efficacy of novel drugs, informing human dosi...

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Bibliographic Details
Main Authors: Rakel Arrazuria, Bernhard Kerscher, Karen E. Huber, Jennifer L. Hoover, Carina Vingsbo Lundberg, Jon Ulf Hansen, Sylvie Sordello, Stephane Renard, Vincent Aranzana-Climent, Diarmaid Hughes, Philip Gribbon, Lena E. Friberg, Isabelle Bekeredjian-Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Microbiology
Subjects:
murine pneumonia model
antimicrobial
lung infection
Gram-negative
PK/PD
antimicrobial efficacy studies
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.988725/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2022.988725/full

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