The mode of action of recombinant Mycobacterium tuberculosis shikimate kinase: kinetics and thermodynamics analyses.

The mode of action of recombinant Mycobacterium tuberculosis shikimate kinase: kinetics and thermodynamics analyses.

Tuberculosis remains as one of the main cause of mortality worldwide due to a single infectious agent, Mycobacterium tuberculosis. The aroK-encoded M. tuberculosis Shikimate Kinase (MtSK), shown to be essential for survival of bacilli, catalyzes the phosphoryl transfer from ATP to the carbon-3 hydro...

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Bibliographic Details
Main Authors: Leonardo Astolfi Rosado, Igor Bordin Vasconcelos, Mário Sérgio Palma, Vincent Frappier, Rafael Josef Najmanovich, Diógenes Santiago Santos, Luiz Augusto Basso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3646032?pdf=render

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http://europepmc.org/articles/PMC3646032?pdf=render

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