CD28null CD4 T-cell expansions in autoimmune disease suggest a link with cytomegalovirus infection [version 1; peer review: 2 approved]

Immunosenescence is thought to contribute to the increase of autoimmune diseases in older people. Immunosenescence is often associated with the presence of an expanded population of CD4 T cells lacking expression of CD28 (CD28null). These highly cytotoxic CD4 T cells were isolated from disease-affec...

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Bibliographic Details
Main Authors: Aalia Bano, Alejandra Pera, Ahmad Almoukayed, Thomas H.S. Clarke, Sukaina Kirmani, Kevin A. Davies, Florian Kern
Format: Article
Language:English
Published: F1000 Research Ltd 2019-03-01
Series:F1000Research
Online Access:https://f1000research.com/articles/8-327/v1