CD28null CD4 T-cell expansions in autoimmune disease suggest a link with cytomegalovirus infection [version 1; peer review: 2 approved]
Immunosenescence is thought to contribute to the increase of autoimmune diseases in older people. Immunosenescence is often associated with the presence of an expanded population of CD4 T cells lacking expression of CD28 (CD28null). These highly cytotoxic CD4 T cells were isolated from disease-affec...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2019-03-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/8-327/v1 |