Examination of MARCO activity on dendritic cell phenotype and function using a gene knockout mouse.

We have reported the upregulation of MARCO, a member of the class A scavenger receptor family, on the surface of murine and human dendritic cells (DCs) pulsed with tumor lysates. Exposure of murine tumor lysate-pulsed DCs to an anti-MARCO antibody led to loss of dendritic-like processes and enhanced...

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Những tác giả chính: Hiroshi Komine, Lisa Kuhn, Norimasa Matsushita, James J Mulé, Shari Pilon-Thomas
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Public Library of Science (PLoS) 2013-01-01
Loạt:PLoS ONE
Truy cập trực tuyến:http://europepmc.org/articles/PMC3698187?pdf=render