Examination of MARCO activity on dendritic cell phenotype and function using a gene knockout mouse.
We have reported the upregulation of MARCO, a member of the class A scavenger receptor family, on the surface of murine and human dendritic cells (DCs) pulsed with tumor lysates. Exposure of murine tumor lysate-pulsed DCs to an anti-MARCO antibody led to loss of dendritic-like processes and enhanced...
Principais autores: | Hiroshi Komine, Lisa Kuhn, Norimasa Matsushita, James J Mulé, Shari Pilon-Thomas |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Public Library of Science (PLoS)
2013-01-01
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coleção: | PLoS ONE |
Acesso em linha: | http://europepmc.org/articles/PMC3698187?pdf=render |
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