Two-step regulation by matrix Gla protein in brown adipose cell differentiation

Two-step regulation by matrix Gla protein in brown adipose cell differentiation

Objective: Bone morphogenetic protein (BMP) signaling is intricately involved in adipose tissue development. BMP7 together with BMP4 have been implicated in brown adipocyte differentiation but their roles during development remains poorly specified. Matrix Gla protein (MGP) inhibits BMP4 and BMP7 an...

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Bibliographic Details
Main Authors: Li Zhang, Xinjiang Cai, Feiyang Ma, Xiaojing Qiao, Jaden Ji, Jocelyn A. Ma, Laurent Vergnes, Yan Zhao, Yucheng Yao, Xiuju Wu, Kristina I. Boström
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Molecular Metabolism
Subjects:
Brown adipogenic differentiation
Matrix Gla protein (MGP)
Bone morphogenetic protein signaling
Gene deletion
Single-cell sequencing analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877824000012

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http://www.sciencedirect.com/science/article/pii/S2212877824000012

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