Silencing circFTO inhibits malignant phenotype through modulating DUSP4 expression in clear cell renal cell carcinoma

Abstract Clear cell renal cell carcinoma (ccRCC) is the most diagnosed malignancy in kidney. Studies on the role of circular RNAs in kidney cancer are increasing. In this study, we employed high throughput sequencing and tissue micro array to detect and verify one of the key circular RNAs, circFTO,...

Full description

Bibliographic Details
Main Authors: Chen Yang, Yiwen Zang, Siqi Wu, Quan Zhou, Yuxi Ou, Qiang Ding, Hao Wang, Zuquan Xiong
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01138-7