Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat.

Animal studies have shown that stress could induce epigenetic and transcriptomic alterations essential in determining the balance between adaptive or maladaptive responses to stress. We tested the hypothesis that chronic stress in rats deregulates coding and non-coding gene expression in the spinal...

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Bibliographic Details
Main Authors: Sylvie Bradesi, Iordanes Karagiannides, Kyriaki Bakirtzi, Swapna Mahurkar Joshi, Georgios Koukos, Dimitrios Iliopoulos, Charalabos Pothoulakis, Emeran A Mayer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4519289?pdf=render