Structural Analysis and Activity Correlation of Amphiphilic Cyclic Antimicrobial Peptides Derived from the [W<sub>4</sub>R<sub>4</sub>] Scaffold

Structural Analysis and Activity Correlation of Amphiphilic Cyclic Antimicrobial Peptides Derived from the [W<sub>4</sub>R<sub>4</sub>] Scaffold

In our ongoing quest to design effective antimicrobial peptides (AMPs), this study aimed to elucidate the mechanisms governing cyclic amphiphilic AMPs and their interactions with membranes. The objective was to discern the nature of these interactions and understand how peptide sequence and structur...

Full description

Bibliographic Details
Main Authors: Shaima A. El-Mowafi, Anastasia G. Konshina, Eman H. M. Mohammed, Nikolay A. Krylov, Roman G. Efremov, Keykavous Parang
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Molecules
Subjects:
antimicrobial activity
molecular dynamics
membrane
peptide
structure-activity relationship
Online Access:https://www.mdpi.com/1420-3049/28/24/8049

Internet

https://www.mdpi.com/1420-3049/28/24/8049

Similar Items