Comprehensive analysis of bulk, single-cell RNA sequencing, and spatial transcriptomics revealed IER3 for predicting malignant progression and immunotherapy efficacy in glioma

Comprehensive analysis of bulk, single-cell RNA sequencing, and spatial transcriptomics revealed IER3 for predicting malignant progression and immunotherapy efficacy in glioma

Abstract Background As part of stress-triggered molecules, immediate early response 3 (IER3) dysregulation has been reported to sustain pro-oncogenic pathways and precede malignant transformation. However, the role of IER3 in glioma pathology is ill-defined. Methods Immunohistochemistry (IHC) assay...

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Bibliographic Details
Main Authors: Qi Wang, Chunyu Zhang, Ying Pang, Meng Cheng, Rui Wang, Xu Chen, Tongjie Ji, Yuntong Yang, Jing Zhang, Chunlong Zhong
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Cancer Cell International
Subjects:
Glioma
TAMMs
Dabrafenib
Prognosis
Immunotherapy
Online Access:https://doi.org/10.1186/s12935-024-03511-1

Internet

https://doi.org/10.1186/s12935-024-03511-1

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