C-peptide enhances glucagon secretion in response to hyperinsulinemia under euglycemic and hypoglycemic conditions

Several studies have associated the presence of residual insulin secretion capability (also referred to as being C-peptide positive) with lower risk of insulin-induced hypoglycemia in patients with type 1 diabetes (T1D), although the reason is unclear. We tested the hypothesis that C-peptide infusio...

Full description

Bibliographic Details
Main Authors: Mary Courtney Moore, Shana O. Warner, Yufei Dai, Nicole Sheanon, Marta Smith, Ben Farmer, Rebecca L. Cason, Alan D. Cherrington, Jason J. Winnick
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-06-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.148997