Single-Molecule Imaging Reveals Rapid Estradiol Action on the Surface Movement of AMPA Receptors in Live Neurons

Single-Molecule Imaging Reveals Rapid Estradiol Action on the Surface Movement of AMPA Receptors in Live Neurons

Gonadal steroid 17β-estradiol (E2) exerts rapid, non-genomic effects on neurons and strictly regulates learning and memory through altering glutamatergic neurotransmission and synaptic plasticity. However, its non-genomic effects on AMPARs are not well understood. Here, we analyzed the rapid effect...

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Bibliographic Details
Main Authors: Soma Godó, Klaudia Barabás, Ferenc Lengyel, Dávid Ernszt, Tamás Kovács, Miklós Kecskés, Csaba Varga, Tibor Z. Jánosi, Géza Makkai, Gergely Kovács, Barbara Orsolits, Takahiro Fujiwara, Akihiro Kusumi, István M. Ábrahám
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
17β-estradiol
AMPAR
single-molecule tracking
diffusion
synapse
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.708715/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.708715/full

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