Site-Specific Variation in Familial Cancer as Suggested by Family History, Multiple Primary Cancer, Age at Onset, and Sex Ratio Associated With Upper, Middle, and Lower Third Esophageal and Gastric Cardia Carcinoma

Site-Specific Variation in Familial Cancer as Suggested by Family History, Multiple Primary Cancer, Age at Onset, and Sex Ratio Associated With Upper, Middle, and Lower Third Esophageal and Gastric Cardia Carcinoma

BackgroundIn China, esophageal squamous cell carcinoma (ESCC) and gastric cardia adenocarcinoma (GCA) differ in terms of multiple primary cancer (MPC) and male-to-female sex ratio (MFSR).MethodsWe studied site-specific variation in familial cancer by comparing family history (FH), MPC, age at onset...

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Bibliographic Details
Main Authors: Denggui Wen, Junpeng Wen, Wendi Zou, Yi Yang, Xiaoduo Wen, Yuetong Chen, Kohei Akazawa, Cuizhi Geng, Baoen Shan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
familial cancer
esophageal squamous cell carcinoma
gastric cardia adenocarcinoma
multiple primary cancer
median onset age
family history of cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.579379/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.579379/full

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