Changes in Day/Night Activity in the 6-OHDA-Induced Experimental Model of Parkinson’s Disease: Exploring Prodromal Biomarkers

Changes in Day/Night Activity in the 6-OHDA-Induced Experimental Model of Parkinson’s Disease: Exploring Prodromal Biomarkers

The search for experimental models mimicking an early stage of Parkinson’s disease (PD) before motor manifestations is fundamental in order to explore early signs and get a better prognosis. Interestingly, our previous studies have indicated that 6-hydroxydopamine (6-OHDA) is a suitable model to ind...

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Bibliographic Details
Main Authors: Catalina Requejo, Karmele López-de-Ipiña, José Ángel Ruiz-Ortega, Elsa Fernández, Pilar M. Calvo, Teresa Morera-Herreras, Cristina Miguelez, Laura Cardona-Grifoll, Hodei Cepeda, Luisa Ugedo, José Vicente Lafuente
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Neuroscience
Subjects:
6-hydroxydopamine
circadian rhythms
home-cage monitoring system
prodromal biomarkers
prodromal Parkinson’s disease symptoms
behavior
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.590029/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2020.590029/full

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