Anti-inflammatory impact of minocycline in a mouse model of tauopathy
Alzheimer’s disease (AD) is characterised by the extracellular deposition of β-amyloid in senile plaques, the intraneuronal accumulation of hyperphosphorylated tau aggregates as neurofibrillary tangles, and progressive neuronal loss leading to the onset of dementia. Increasing evidence suggests that...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2010-10-01
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Series: | Frontiers in Psychiatry |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpsyt.2010.00136/full |