GPR34 in spinal microglia exacerbates neuropathic pain in mice

GPR34 in spinal microglia exacerbates neuropathic pain in mice

Abstract Background Neuropathic pain is caused by sensory nerve injury, but effective treatments are currently lacking. Microglia are activated in the spinal dorsal horn after sensory nerve injury and contribute to neuropathic pain. Accordingly, molecules expressed by these cells are considered pote...

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Bibliographic Details
Main Authors: Akira Sayo, Hiroyuki Konishi, Masaaki Kobayashi, Kuniyuki Kano, Hiroki Kobayashi, Hideharu Hibi, Junken Aoki, Hiroshi Kiyama
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Neuroinflammation
Subjects:
Allodynia
GPCR
GPR34
LysoPS
Microglia
Neuroinflammation
Online Access:http://link.springer.com/article/10.1186/s12974-019-1458-8

Internet

http://link.springer.com/article/10.1186/s12974-019-1458-8

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