Extreme evolutionary conservation of functionally important regions in H1N1 influenza proteome.

The H1N1 subtype of influenza A virus has caused two of the four documented pandemics and is responsible for seasonal epidemic outbreaks, presenting a continuous threat to public health. Co-circulating antigenically divergent influenza strains significantly complicates vaccine development and use. H...

Full description

Bibliographic Details
Main Authors: Samantha Warren, Xiu-Feng Wan, Gavin Conant, Dmitry Korkin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3839886?pdf=render