PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors

Summary: Development is regulated by various factors, including protein methylation status. While PRMT5 is well known for its roles in oncogenesis by mediating symmetric di-methylation of arginine, its role in normal development remains elusive. Using Myod1Cre to drive Prmt5 knockout in embryonic my...

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Bibliographic Details
Main Authors: Kun Ho Kim, Stephanie N. Oprescu, Madigan M. Snyder, Aran Kim, Zhihao Jia, Feng Yue, Shihuan Kuang
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723013414