Cross-reactive MHC class I T cell epitopes may dictate heterologous immune responses between respiratory viruses and food allergens

Abstract Respiratory virus infections play a major role in asthma, while there is a close correlation between asthma and food allergy. We hypothesized that T cell-mediated heterologous immunity may induce asthma symptoms among sensitized individuals and used two independent in silico pipelines for t...

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Bibliographic Details
Main Authors: Kathrin Balz, Abhinav Kaushik, Franz Cemic, Vanitha Sampath, Vanessa Heger, Harald Renz, Kari Nadeau, Chrysanthi Skevaki
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41187-1