DNMT1 is a negative regulator of osteogenesis

DNMT1 is a negative regulator of osteogenesis

The role and underlying mechanisms of DNA methylation in osteogenesis/chondrogenesis remain poorly understood. We here reveal DNA methyltransferase 1 (DNMT1), which is responsible for copying DNA methylation onto the newly synthesized DNA strand after DNA replication, is overexpressed in sponge bone...

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Bibliographic Details
Main Authors: Chen Tao, Jia Liu, Ziqi Li, Pinglin Lai, Sheng Zhang, Jiankun Qu, Yujin Tang, Anling Liu, Zhipeng Zou, Xiaochun Bai, Jianwei Li
Format: Article
Language:English
Published: The Company of Biologists 2022-03-01
Series:Biology Open
Subjects:
dnmt1
msc
osteoblast
methylation
Online Access:http://bio.biologists.org/content/11/3/bio058534

Internet

http://bio.biologists.org/content/11/3/bio058534

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