First‐Trimester Maternal Folic Acid Supplementation Reduced Risks of Severe and Most Congenital Heart Diseases in Offspring: A Large Case‐Control Study

First‐Trimester Maternal Folic Acid Supplementation Reduced Risks of Severe and Most Congenital Heart Diseases in Offspring: A Large Case‐Control Study

Background Maternal folic acid supplementation (FAS) reduces the risk of neural tube defects in offspring. However, its effect on congenital heart disease (CHDs), especially on the severe ones remains uncertain. This study aimed to assess the individual and joint effect of first‐trimester maternal F...

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Bibliographic Details
Main Authors: Yanji Qu, Shao Lin, Jian Zhuang, Michael S. Bloom, Maggie Smith, Zhiqiang Nie, Jinzhuang Mai, Yanqiu Ou, Yong Wu, Xiangmin Gao, Hongzhuan Tan, Xiaoqing Liu
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
congenital heart disease
folate
multivitamin
pregnancy
prevention
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.015652

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.119.015652

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