AMPK-endoplasmic reticulum stress axis contributes to lipopolysaccharide-caused mitochondrial dysfunction by regulating mitochondria-associated membrane function in bovine hepatocytes

AMPK-endoplasmic reticulum stress axis contributes to lipopolysaccharide-caused mitochondrial dysfunction by regulating mitochondria-associated membrane function in bovine hepatocytes

ABSTRACT: Mitochondrial homeostasis is closely associated with cellular homeostasis process, whereas mitochondrial dysfunction contributes to apoptosis and mitophagy. Hence, analyzing the mechanism of lipopolysaccharide (LPS)-caused mitochondrial damage is necessary to understand how cellular homeos...

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Bibliographic Details
Main Authors: Wan Xie, Mengru Chen, Juan J. Loor, Xiaokun Song, Nana Ma, Shendong Zhou, Hongzhu Zhang, Guangjun Chang, Xiangzhen Shen
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Journal of Dairy Science
Subjects:
mitochondrial dysfunction
adenosine 5′-monophosphate-activated protein kinase
endoplasmic reticulum stress
mitochondria-associated membranes
bovine hepatocytes
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030223002758

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http://www.sciencedirect.com/science/article/pii/S0022030223002758

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