Tyrosine kinase receptor inhibitor-targeted combined chemotherapy for metastatic bladder cancer

Overexpression of hypoxia-inducible factor-1 alpha is noted during the invasive and metastatic process of transitional cell carcinoma. It will upregulate vascular endothelial growth factor (VEGF) and drive proliferation, invasiveness, metastasis, and antiapoptotic ability of cancer cells. We propose...

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Bibliographic Details
Main Authors: Chia-Lun Wu, Szu-Yuan Ping, Cheng-Ping Yu, Dah-Shyong Yu
Format: Article
Language:English
Published: Wiley 2012-04-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X11001410