Low-dose arecoline regulates distinct core signaling pathways in oral submucous fibrosis and oral squamous cell carcinoma

Low-dose arecoline regulates distinct core signaling pathways in oral submucous fibrosis and oral squamous cell carcinoma

Abstract Background Betel nut chewing plays a role in the pathogenesis of oral submucous fibrosis (OSF) and oral squamous cell carcinoma (OSCC). As the major active ingredient of the betel nut, the effect of arecoline and its underlying mechanism to OSF and OSCC pathogenesis remain unclear. Methods...

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Bibliographic Details
Main Authors: Zhenming Li, You Fu, Yuhua Hu, Yun Zhu, Longwei Hu, Chaoji Shi, Yi Zhang, Jianjun Zhang, Shanghui Zhou
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Oral Health
Subjects:
Arecoline
OPMD
OSF
OSCC
Malignant progression
Online Access:https://doi.org/10.1186/s12903-023-02887-2

Internet

https://doi.org/10.1186/s12903-023-02887-2

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