Foretinib mitigates cutaneous nerve fiber loss in experimental diabetic neuropathy

Abstract Diabetes is by far, the most common cause of neuropathy, inducing neurodegeneration of terminal sensory nerve fibers associated with loss of sensation, paresthesia, and persistent pain. Foretinib prevents die-back degeneration in cultured sensory and sympathetic neurons by rescuing mitochon...

Full description

Bibliographic Details
Main Authors: Simeon C. Daeschler, Jennifer Zhang, Tessa Gordon, Gregory H. Borschel, Konstantin Feinberg
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12455-3