Mitochondrial DNA Damage Does Not Determine C. elegans Lifespan

Mitochondrial DNA Damage Does Not Determine C. elegans Lifespan

The mitochondrial free radical theory of aging (mFRTA) proposes that accumulation of oxidative damage to macromolecules in mitochondria is a causative mechanism for aging. Accumulation of mitochondrial DNA (mtDNA) damage may be of particular interest in this context. While there is evidence for age-...

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Bibliografische gegevens
Hoofdauteurs: Li Fang Ng, Li Theng Ng, Michiel van Breugel, Barry Halliwell, Jan Gruber
Formaat: Artikel
Taal:English
Gepubliceerd in: Frontiers Media S.A. 2019-04-01
Reeks:Frontiers in Genetics
Onderwerpen:
mitochondrial DNA
DNA damage
lifespan
healthspan
aging
hormesis
Online toegang:https://www.frontiersin.org/article/10.3389/fgene.2019.00311/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00311/full

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