Evaluation of the Effect of CD70 Co-Expression on CD8 T Cell Response in Protein-Prime MVA-Boost Vaccination in Mice

Evaluation of the Effect of CD70 Co-Expression on CD8 T Cell Response in Protein-Prime MVA-Boost Vaccination in Mice

Here, we investigate the potential of CD70 co-expression during viral vector boost vaccination to improve an antigen-specific T cell response. To determine the chance of activating antigen-specific T cells by CD70, we used the HBV core antigen as a model antigen in a heterologous protein-prime, Modi...

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Bibliographic Details
Main Authors: Ann-Sophie Stephan, Anna D. Kosinska, Martin Mück-Häusl, Andreas Muschaweckh, Clemens Jäger, Natalie Röder, Mathias Heikenwälder, Claudia Dembek, Ulrike Protzer
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Vaccines
Subjects:
hepatitis B virus
vaccines
immune therapy
CD70
Online Access:https://www.mdpi.com/2076-393X/11/2/245

Internet

https://www.mdpi.com/2076-393X/11/2/245

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