Helical peptides with disordered regions for measles viruses provide new generalized insights into fusion inhibitors

Summary: Despite effective vaccines, measles virus (MeV) outbreaks occur sporadically. Therefore, developing anti-MeV agents remains important for suppressing MeV infections. We previously designed peptide-based MeV fusion inhibitors, M1 and M2, that target MeV class I fusion protein (F protein). He...

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Bibliographic Details
Main Authors: Kazushige Hirata, Aoi Takahara, Satoshi Suzuki, Shumei Murakami, Kumi Kawaji, Akie Nishiyama, Mina Sasano, Mariko Shoji-Ueno, Emiko Usui, Kazutaka Murayama, Hironori Hayashi, Shinya Oishi, Eiichi N. Kodama
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224001822