Residual Proviral Reservoirs: A High Risk for HIV Persistence and Driving Forces for Viral Rebound after Analytical Treatment Interruption

Antiretroviral therapy (ART) has dramatically suppressed human immunodeficiency virus (HIV) replication and become undetectable viremia. However, a small number of residual replication-competent HIV proviruses can still persist in a latent state even with lifelong ART, fueling viral rebound in HIV-i...

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Bibliographic Details
Main Authors: Xiaolei Wang, Huanbin Xu
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/2/335