Short-Term Instantaneous Prophylaxis and Efficient Treatment Against SARS-CoV-2 in hACE2 Mice Conferred by an Intranasal Nanobody (Nb22)

Short-Term Instantaneous Prophylaxis and Efficient Treatment Against SARS-CoV-2 in hACE2 Mice Conferred by an Intranasal Nanobody (Nb22)

Current COVID-19 vaccines need to take at least one month to complete inoculation and then become effective. Around 51% of the global population is still not fully vaccinated. Instantaneous protection is an unmet need among those who are not fully vaccinated. In addition, breakthrough infections cau...

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Bibliographic Details
Main Authors: Xilin Wu, Yaxing Wang, Lin Cheng, Fengfeng Ni, Linjing Zhu, Sen Ma, Bilian Huang, Mengmeng Ji, Huimin Hu, Yuncheng Li, Shijie Xu, Haixia Shi, Doudou Zhang, Linshuo Liu, Waqas Nawaz, Qinxue Hu, Sheng Ye, Yalan Liu, Zhiwei Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
Delta variant
nanobody
Nb22
STIP
structure
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.865401/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.865401/full

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