Neuregulin (NRG-1β) Is Pro-Myogenic and Anti-Cachectic in Respiratory Muscles of Post-Myocardial Infarcted Swine

Neuregulin-1β (NRG-1β) is a growth and differentiation factor with pleiotropic systemic effects. Because NRG-1β has therapeutic potential for heart failure and has known growth effects in skeletal muscle, we hypothesized that it might affect heart failure-associated cachexia, a severe co-morbidity c...

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Bibliographic Details
Main Authors: Cristi L. Galindo, Van Thuan Nguyen, Braxton Hill, Ethan Easterday, John H. Cleator, Douglas B. Sawyer
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/11/5/682