Hyaluronic acid-alendronate conjugate: A macromolecular drug delivery system for intra-articular treatment of osteoarthritis

Hyaluronic acid-alendronate conjugate: A macromolecular drug delivery system for intra-articular treatment of osteoarthritis

Objective: Osteoarthritis (OA) is a painful degenerative disease of the whole joint structure, including articular cartilage, synovial fluid, and subchondral bone. Hyaluronic acid (HA), an anionic non-sulfated glycosaminoglycan, is commonly used for intra-articular (IA) treatment in OA, while bispho...

Full description

Bibliographic Details
Main Authors: Stefano Pluda, Riccardo Beninatto, Matteo Soato, Carlo Barbera, Alba di Lucia, Lidia Fassina, Filippo Gatti, Cristian Guarise, Devis Galesso, Mauro Pavan
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Hyaluronan
Bisphosphonate
Osteoarthritis
Intra-articular
Alendronate
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913121000224

Internet

http://www.sciencedirect.com/science/article/pii/S2665913121000224

Similar Items