β-cell intrinsic dynamics rather than gap junction structure dictates subpopulations in the islet functional network
Diabetes is caused by the inability of electrically coupled, functionally heterogeneous β-cells within the pancreatic islet to provide adequate insulin secretion. Functional networks have been used to represent synchronized oscillatory [Ca2+] dynamics and to study β-cell subpopulations, which play a...
| Glavni autori: | , , , , , , |
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| Format: | Članak |
| Jezik: | English |
| Izdano: |
eLife Sciences Publications Ltd
2023-11-01
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| Serija: | eLife |
| Teme: | |
| Online pristup: | https://elifesciences.org/articles/83147 |