Genome‐scale engineering for systems and synthetic biology
Genome‐modification technologies enable the rational engineering and perturbation of biological systems. Historically, these methods have been limited to gene insertions or mutations at random or at a few pre‐defined locations across the genome. The handful of methods capable of targeted gene editin...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2013-01-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.1038/msb.2012.66 |