Genome‐scale engineering for systems and synthetic biology

Genome‐modification technologies enable the rational engineering and perturbation of biological systems. Historically, these methods have been limited to gene insertions or mutations at random or at a few pre‐defined locations across the genome. The handful of methods capable of targeted gene editin...

Full description

Bibliographic Details
Main Authors: Kevin M Esvelt, Harris H Wang
Format: Article
Language:English
Published: Springer Nature 2013-01-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/msb.2012.66