Machine learning model reveals the risk, prognosis, and drug response of histamine-related signatures in pancreatic cancer

Abstract Background Histamine, a critical inflammatory mediator, is generated by both mast cells and specific tumor cells, and it plays a fundamental role in inflammatory and immune responses. In the current scientific landscape, histamine-related genes (HRGs) and their associated pathways have been...

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Bibliographic Details
Main Authors: Chang-Lei Li, Zhi-Yuan Yao, Chao Qu, Guan-Ming Shao, Yu-Kun Liu, Xiang-Yu Pei, Jing-Yu Cao, Zu-Sen Wang
Format: Article
Language:English
Published: Springer 2025-02-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-01910-y