An In-Silico Identification of Potential Flavonoids against Kidney Fibrosis Targeting TGFβR-1

An In-Silico Identification of Potential Flavonoids against Kidney Fibrosis Targeting TGFβR-1

Fibrosis is a hallmark of progressive kidney diseases. The overexpression of profibrotic cytokine, namely transforming growth factor β (TGF-β) due to excessive inflammation and tissue damage, induces kidney fibrosis. The inhibition of TGF-β signaling is markedly limited in experimental disease model...

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Bibliographic Details
Main Authors: MD. Hasanur Rahman, Partha Biswas, Dipta Dey, Md. Abdul Hannan, Md. Sahabuddin, Yusha Araf, Youngjoo Kwon, Talha Bin Emran, Md. Sarafat Ali, Md Jamal Uddin
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Life
Subjects:
kidney fibrosis
chronic kidney disease
TGFβR-1
flavonoids
pharmacokinetics
molecular docking
Online Access:https://www.mdpi.com/2075-1729/12/11/1764

Internet

https://www.mdpi.com/2075-1729/12/11/1764

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