The circadian regulator PER1 promotes cell reprogramming by inhibiting inflammatory signaling from macrophages.

Circadian regulation of gene expression is prevalent and plays critical roles in cell differentiation. However, its roles in the reprogramming of differentiated cells remain largely unknown. Here, we found that one of the master circadian regulators PER1 promoted virus-mediated reprogramming of mous...

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Bibliographic Details
Main Authors: Nobuko Katoku-Kikyo, Seunghyun Lim, Ce Yuan, Jinsha Koroth, Yasushi Nakagawa, Elizabeth W Bradley, Nobuaki Kikyo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-12-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002419&type=printable