Limited wedge resection for T1 colon cancer (LIMERIC-II trial) – rationale and study protocol of a prospective multicenter clinical trial

Abstract Background The sole presence of deep submucosal invasion is shown to be associated with a limited risk of lymph node metastasis. This justifies a local excision of suspected deep submucosal invasive colon carcinomas (T1 CCs) as a first step treatment strategy. Recently Colonoscopy-Assisted...

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Main Authors: Julia Hanevelt, Jelle F. Huisman, Laura W. Leicher, Miangela M. Lacle, Milan C. Richir, Paul Didden, Joost M. J. Geesing, Niels Smakman, Jochim S. Terhaar Sive Droste, Frank ter Borg, A. Koen Talsma, Ruud W. M. Schrauwen, Bob J. van Wely, Ingrid Schot, Maarten Vermaas, Philip Bos, Colin Sietses, Wouter L. Hazen, Dareczka K. Wasowicz, David E. Ploeg, Dewkoemar Ramsoekh, Jurriaan B. Tuynman, Yasser A. Alderlieste, Rutger-Jan Renger, Ramon-Michel Schreuder, Johanne G. Bloemen, Ineke van Lijnschoten, Esther C. J. Consten, Daan J. Sikkenk, Matthijs P. Schwartz, Annelotte Vos, Jordy P. W. Burger, Bernhard W. M. Spanier, Nikki Knijn, Wouter H. de Vos Tot Nederveen Cappel, Leon M. G. Moons, Henderik L. van Westreenen
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Gastroenterology
Subjects:
Online Access:https://doi.org/10.1186/s12876-023-02854-9