Functional Proteomics Characterization of the Role of SPRYD7 in Colorectal Cancer Progression and Metastasis

Functional Proteomics Characterization of the Role of SPRYD7 in Colorectal Cancer Progression and Metastasis

SPRY domain-containing protein 7 (SPRYD7) is a barely known protein identified via spatial proteomics as being upregulated in highly metastatic-to-liver KM12SM colorectal cancer (CRC) cells in comparison to its isogenic poorly metastatic KM12C CRC cells. Here, we aimed to analyze SPRYD7’s role in CR...

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Bibliographic Details
Main Authors: Ana Montero-Calle, Sofía Jiménez de Ocaña, Ruth Benavente-Naranjo, Raquel Rejas-González, Rubén A. Bartolomé, Javier Martínez-Useros, Rodrigo Sanz, Jana Dziaková, María Jesús Fernández-Aceñero, Marta Mendiola, José Ignacio Casal, Alberto Peláez-García, Rodrigo Barderas
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cells
Subjects:
colorectal cancer
SPRYD7
cancer metastasis
proteomics
protein dysregulation
interactome
Online Access:https://www.mdpi.com/2073-4409/12/21/2548

Internet

https://www.mdpi.com/2073-4409/12/21/2548

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