SNA077, an Extract of Marine <i>Streptomyces</i> sp., Inhibits Melanogenesis by Downregulating Melanogenic Proteins via Inactivation of cAMP/PKA/CREB Signaling

Excess melanin in skin is known to be the main cause of hyper-pigmentary skin diseases such as freckles and lentigo. This study aimed to evaluate the depigmenting efficacy of an extract from the marine microorganism strain, <i>Streptomyces</i> sp. SNA077. To determine the anti-melanogeni...

Full description

Bibliographic Details
Main Authors: Su-Jin Lim, Da-Won Jung, Prima F. Hillman, Sang-Jip Nam, Chang-Seok Lee
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/23/14922